MYOCD

Also known as MYCD, myocardin, MGBL

Myocardin is a protein that in humans is encoded by the MYOCD gene.

Gene data

MYOCD

Name: myocardin
Type: protein-coding
Aliases: MGBL, MYCD

This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].

via MyGene.info

Wikidata facts

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HomoloGene ID: 17043
exact match: identifiers.org/ncbigene/93649
genomic end: 12672266
genomic start: 12569207
cytogenetic location: 17p12

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Contents

Structure
Function
Gene
References
Further reading

Myocardin is a protein that in humans is encoded by the MYOCD gene.

Myocardin is a smooth muscle cell and cardiac muscle cell-specific transcriptional coactivator of serum response factor (SRF). When expressed in smooth muscle precursor cells and abnormally in nonmuscle cells, myocardin can induce smooth muscle cell differentiation. Myocardin can also function in the differentiation of myocardial cells.