نيترازيبام

Key facts

Drug.Verifiedfields

changed

Drug.Watchedfields

changed

Drug.verifiedrevid

461743504

Drug.IUPAC_name

7-nitro-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Drug.image

Nitrazepam.svg

Drug.image_class

skin-invert-image

Drug.width

222

Drug.image2

Nitrazepam-from-xtal-3D-balls.png

Drug.image_class2

bg-transparent

Drug.tradename

Alodorm, Apodorm, Arem, Cerson, Insoma, Insomin, Mogadon, Nitrados, Nitrazadon, Nitrosun, Nitravet, Ormodon, Paxadorm, Remnos, Epam, and Somnite

Drug.dependency_liability

Physical: High Psychological: Moderate

Drug.addiction_liability

Moderate

Drug.pregnancy_US

D

Drug.legal_BR

B1

Drug.legal_CA

Schedule IV

Drug.legal_AU

Schedule 4

Drug.legal_DE

Rx-only/Anlage III

Drug.legal_UN

Psychotropic Schedule IV

via Wikipedia infobox

Chemical data

Formula

C15H11N3O3

Molecular weight

281.27 g/mol

IUPAC name

7-nitro-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one

SMILES

C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3

InChIKey

KJONHKAYOJNZEC-UHFFFAOYSA-N

XLogP

2.2

Polar surface area

87.3 Ų

H-bond donors

1

H-bond acceptors

4

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

Indications

epilepsy, anxiety, Dementia, depressive disorder

via ChEMBL · EBI

• Clinical pharmacokinetics of nitrazepam.Clinical pharmacokinetics · 1981
• [Clonazepam, nitrazepam, diazepam].Nihon rinsho. Japanese journal of clinical medicine · 1995
• Nitrazepam (Mogadon) dependence.The British journal of psychiatry : the journal of mental science · 1975
• [Benzodiazepine (clonazepam, nitrazepam, diazepam)].Nihon rinsho. Japanese journal of clinical medicine · 2004
• Nitrazepam nightmares.British medical journal · 1973

via PubMed

Wikidata facts

Subclass of

alkaloid

Mass

281.08

Has use

medication

via Wikidata · CC0