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solriamfetol

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Also known as (R)-2-amino-3-phenylpropyl carbamate, SKL-N05, ARL-N05, ADX-N05, JZP-110, (2R)-2-Amino-3-phenylpropyl carbamate

Solriamfetol, sold under the brand name Sunosi, is a wakefulness-promoting medication used in the treatment of excessive sleepiness related to narcolepsy and sleep apnea. It is taken by mouth.

Key facts

Drug.image
Solriamfetol.svg
Drug.image_class
skin-invert-image
Drug.caption
Molecular structure of solriamfetol
Drug.image2
Solriamfetol 3D.png
Drug.image_class2
bg-transparent
Drug.tradename
Sunosi
Drug.MedlinePlus
a619040
Drug.DailyMedID
Solriamfetol
Drug.routes_of_administration
By mouth
Drug.caption2
3D representation of a solriamfetol molecule
Drug.class
Norepinephrine–dopamine reuptake inhibitor; Wakefulness-promoting agent
Drug.ATC_prefix
N06
Drug.ATC_suffix
BA14
Drug.legal_CA
Rx-only
Drug.legal_US
Schedule IV
Drug.legal_EU
Rx-only
Drug.bioavailability
~95%
Drug.protein_bound
13.3–19.4%

via Wikipedia infobox

~7 min read

Encyclopedic overview

14 sections
Contents
  • Medical uses
  • Available forms
  • Side effects
  • Misuse potential
  • Pharmacology
  • Pharmacodynamics
  • Pharmacokinetics
  • Chemistry
  • History
  • Society and culture
  • Names
  • Legal status
  • Research
  • References

Solriamfetol, sold under the brand name Sunosi, is a wakefulness-promoting medication used in the treatment of excessive sleepiness related to narcolepsy and sleep apnea. It is taken by mouth.

Common side effects of solriamfetol include headache, nausea, anxiety, and trouble sleeping. It is a norepinephrine–dopamine reuptake inhibitor (NDRI) and is thought to work by increasing levels of the neurotransmitters norepinephrine and dopamine in the brain. Solriamfetol has also been found to act as a TAAR1 agonist, an action that may also be involved in its effects.

Excerpted from Wikipedia’s “solriamfetol” article, available under the CC BY-SA 4.0 licence.

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