Noribogaine, also known as '''O-desmethylibogaine or 12-hydroxyibogamine', is the principal psychoactive metabolite of the oneirogen ibogaine. It is thought to be involved in the antiaddictive effects of ibogaine-containing plant extracts, such as Tabernanthe iboga''.
Noribogaine, also known as '''O-desmethylibogaine or 12-hydroxyibogamine', is the principal psychoactive metabolite of the oneirogen ibogaine. It is thought to be involved in the antiaddictive effects of ibogaine-containing plant extracts, such as Tabernanthe iboga''.
The drug appears to have a complex mechanism of action, with many different observed activities. Some of its most potent actions is atypical κ-opioid receptor agonism and serotonin reuptake inhibition. Noribogaine has potent psychoplastogenic effects similarly to ibogaine.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).