normeperidine
Sign in to saveAlso known as norpethidine
Norpethidine (normeperidine, pethidine intermediate B) is a 4-phenylpiperidine derivative that is both a precursor to, and the toxic metabolite of, pethidine (meperidine). It is scheduled by UN Single Convention on Narcotic Drugs. It is a Schedule II Narcotic controlled substance in the United States and has an ACSCN of 9233. The 2014 annual manufacturing quota was .
Research
163 papers- Normeperidine toxicity.Anesthesia and analgesia · 1986
- Recognizing normeperidine toxicity.Nursing · 2003
- Disposition of meperidine and normeperidine following multiple doses during labor. I. Mother.American journal of obstetrics and gynecology · 1985
- Pharmacology.International anesthesiology clinics · 1999
- Clearance of meperidine and its metabolite normeperidine in hemodialysis patients with chronic noncancer pain.Journal of pain and symptom management · 2014
via PubMed
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Encyclopedic overview
3 sectionsContents
- Precursor Use
- See also
- References
Norpethidine (normeperidine, pethidine intermediate B) is a 4-phenylpiperidine derivative that is both a precursor to, and the toxic metabolite of, pethidine (meperidine). It is scheduled by UN Single Convention on Narcotic Drugs. It is a Schedule II Narcotic controlled substance in the United States and has an ACSCN of 9233. The 2014 annual manufacturing quota was .
Norpethidine is a controlled drug because of its potential uses in manufacturing both pethidine itself and a range of N-substituted derivatives, but it has little opioid activity in its own right. Instead, norpethidine acts as a stimulant and causes convulsions.
Excerpted from Wikipedia’s “normeperidine” article, available under the CC BY-SA 4.0 licence.