NSFL1C

Also known as P47, UBX1, UBXD10, UBXN2C, dJ776F14.1, NSFL1 cofactor

NSFL1 cofactor p47 is a protein that in humans is encoded by the NSFL1C gene.

Gene data

NSFL1C

Name: NSFL1 cofactor
Type: protein-coding
Aliases: P47, UBX1, UBXD10, UBXN2C, dJ776F14.1

N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, May 2011].

via MyGene.info

Wikidata facts

Image: Protein NSFL1C PDB 1i42.png

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HomoloGene ID: 41114
exact match: identifiers.org/ncbigene/55968
genomic end: 1454487
genomic start: 1422807
cytogenetic location: 20p13
Commons category: NSFL1C

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NSFL1 cofactor p47 is a protein that in humans is encoded by the NSFL1C gene.

N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Multiple transcript variants encoding several different isoforms have been found for this gene.