ODAD4

Also known as tetratricopeptide repeat domain 25, TTC25, outer dynein arm docking complex subunit 4

Tetratricopeptide repeat protein 25 is a protein that in humans is encoded by the TTC25 gene.

Gene data

ODAD4

Name: outer dynein arm docking complex subunit 4
Type: protein-coding
Aliases: TTC25

This gene encodes a tetratricopeptide repeat domain-containing protein that localizes to ciliary axonmenes and plays a role in the docking of the outer dynein arm to cilia. Mutations in this gene cause severely reduced ciliary motility and the disorder CILD35 (ciliary dyskinesia,primary, 35). Primary ciliary dyskinesia is often associated with recurrent respiratory infections, immotile spermatozoa, and situs inversus; an inversion in left-right body symmetry. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017].

via MyGene.info