OPA3

Also known as MGA3, optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia), OPA3, outer mitochondrial membrane lipid metabolism regulator, OPA3 outer mitochondrial membrane lipid metabolism regulator, outer mitochondrial membrane lipid metabolism regulator OPA3

gene umano

In the Vinony graph

Vinony's link graph records 5 inbound references to OPA3, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 19.

Vinony links it to 6 Wikipedia language editions.

Gene data

OPA3

Name: outer mitochondrial membrane lipid metabolism regulator OPA3
Type: protein-coding
Position: 45,527,767–45,602,212 (−)
Aliases: MGA3
Ensembl: ENSG00000125741
RefSeq RNA: NM_001017989.3, NM_025136.4, XM_006723403.5, XM_054322228.1
RefSeq protein: NP_001017989.2, NP_079412.1, XP_006723466.1, XP_054178203.1

The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].