OPCML

Also known as IGLON1, OBCAM, OPCM, opioid binding protein/cell adhesion molecule-like, opioid binding protein/cell adhesion molecule like

Opioid-binding protein/cell adhesion molecule is a protein that in humans is encoded by the OPCML gene.

Gene data

OPCML

Name: opioid binding protein/cell adhesion molecule like
Type: protein-coding
Aliases: IGLON1, OBCAM, OPCM

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016].

via MyGene.info

Gene · Ensembl

opioid binding protein/cell adhesion molecule like

Symbol: OPCML
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:132,414,977-133,532,539
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 55663
exact match: identifiers.org/ncbigene/4978
genomic end: 133532501
genomic start: 132284871
cytogenetic location: 11q25

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Opioid-binding protein/cell adhesion molecule is a protein that in humans is encoded by the OPCML gene.

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the cell membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene.