CD5 antigen-like is a protein (also known as AIM, for apoptosis inhibitor of macrophage) that in humans is encoded by the CD5L gene. It is expressed by macrophages. It regulates immune responses and inflammation. It plays a crucial role in key intracellular processes like lipid metabolism and apoptosis.
CD5 antigen-like is a protein (also known as AIM, for apoptosis inhibitor of macrophage) that in humans is encoded by the CD5L gene. It is expressed by macrophages. It regulates immune responses and inflammation. It plays a crucial role in key intracellular processes like lipid metabolism and apoptosis.
==Gene== AIM, also known as apoptosis inhibitor of macrophage, is a 40 kDa protein encoded by the CD5L gene. Its expression is predominantly driven by tissue-resident macrophages via transcriptional activation of nuclear receptors such as LXR and RXR, and/or the transcription factor MAFB. Expression is further regulated by GSK3 through activation of STAT3, which influences CD5L promoter activity.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).