ADGRA3
Sign in to saveAlso known as PGR21, TEM5L, GPR125, adhesion G protein-coupled receptor A3
Adhesion G-protein coupled receptor A3 (ADGRA3), also known as GPR125, is an adhesion GPCR that in humans is encoded by the Adgra3 gene (previously Gpr125).
Gene data
ADGRA3- Name
- adhesion G protein-coupled receptor A3
- Type
- protein-coding
- Position
- 22,345,071–22,516,131 (−)
- Aliases
- GPR125, PGR21, TEM5L
- Ensembl
- ENSG00000152990
- RefSeq RNA
- NM_145290.4, XM_005248137.6, XM_011513811.3, XM_047449703.1, XM_047449704.1
- RefSeq protein
- NP_660333.2, XP_005248194.1, XP_011512113.1, XP_047305659.1, XP_047305660.1
This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Wikidata facts
- Instance of
- gene
Show 4 more facts
- HomoloGene ID
- 19235
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/166647
- cytogenetic location
- 4p15.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Adhesion G-protein coupled receptor A3 (ADGRA3), also known as GPR125, is an adhesion GPCR that in humans is encoded by the Adgra3 gene (previously Gpr125).
==References==
Excerpted from Wikipedia’s “ADGRA3” article, available under the CC BY-SA 4.0 licence.