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GeneQ18038302· pop 7· linked from 2 articles

OSTF1

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Also known as OSF, SH3P2, bA235O14.1, osteoclast stimulating factor 1

Osteoclast-stimulating factor 1 is a protein that in humans is encoded by the OSTF1 gene.

Gene data

OSTF1

Name: osteoclast stimulating factor 1
Type: protein-coding
Position: 75,088,480–75,149,429 (+)
Aliases: OSF, SH3P2, bA235O14.1
Ensembl: ENSG00000134996
RefSeq RNA: NM_012383.5, XM_006717053.4, XM_006717055.4, XM_011518524.3, XM_011518525.4
RefSeq protein: NP_036515.4, XP_006717116.1, XP_006717118.1, XP_011516826.1, XP_011516827.1

Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).[supplied by OMIM, Mar 2008].

Gene Ontology

Biological process

ossification signal transduction signal transduction

Molecular function

protein binding SH3 domain binding

Cellular component

extracellular region extracellular region cytoplasm cytosol secretory granule lumen ficolin-1-rich granule lumen

Pathways

Innate Immune System Immune System Neutrophil degranulation

via MyGene.info

Wikidata facts

Image: Protein OSTF1 PDB 1x2k.png

Show 5 more facts

HomoloGene ID: 8227
exact match: identifiers.org/ncbigene/26578
genomic end: 77762181
genomic start: 75088514
cytogenetic location: 9q21.13

Sources (4)

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Contents

References
Further reading

Osteoclast-stimulating factor 1 is a protein that in humans is encoded by the OSTF1 gene.

==References==

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Categories

Genes on human chromosome 9