OSBPL1A
Sign in to saveAlso known as ORP-1, ORP1, OSBPL1B, oxysterol binding protein like 1A
Oxysterol-binding protein-related protein 1 is a protein that in humans is encoded by the OSBPL1A gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to OSBPL1A, and connects out to PubMed, human chromosome 18 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 18.
Vinony links it to 5 Wikipedia language editions.
Gene data
OSBPL1A- Name
- oxysterol binding protein like 1A
- Type
- protein-coding
- Position
- 24,162,045–24,397,908 (−)
- Aliases
- ORP-1, ORP1, OSBPL1B
- Ensembl
- ENSG00000141447
- RefSeq RNA
- NM_001242508.1, NM_018030.4, NM_080597.4, NM_133268.1, XM_017025530.2
- RefSeq protein
- NP_001229437.1, NP_060500.3, NP_542164.2, XP_016881019.1, XP_047293243.1
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
oxysterol binding protein like 1A
- Symbol
- OSBPL1A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:24,162,045-24,397,908
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 84746
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/114876
- genomic end
- 21977844
- genomic start
- 24162045
- chromosome
- human chromosome 18
- cytogenetic location
- 18q11.2
- expressed in
- occipital lobe
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Oxysterol-binding protein-related protein 1 is a protein that in humans is encoded by the OSBPL1A gene.
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms.
Excerpted from Wikipedia’s “OSBPL1A” article, available under the CC BY-SA 4.0 licence.