оксикодон

Also known as dihydroxycodeinone, dihydrohydroxycodeinone, dihydro-14-hydroxycodeinone, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one, (-)-14-hydroxydihydrocodeinone, 4,5α-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one, Oxycontin

обезболивающий препарат, полусинтетический опиоид, получаемый из тебаина

OverviewAI-generated

Oxycodone is a chemical compound with the formula C₁₈H₂₁NO₄. It was discovered in 1916. The substance has a mass of 315.147 and a weight of 315.4. Its IUPAC name is (4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.

The compound has a defined daily dose of 75. It carries a charge of 0, with an xlogp of 1.2 and a topological polar surface area of 59. Oxycodone features one hydrogen bond donor and five hydrogen bond acceptors. Stylized names for the substance include "oxyCODONE" and "OxyCONTIN".

Oxycodone is referenced by 1,646 other encyclopedia articles. A PubMed query for oxycodone returns a count of 6,111 entries.

Synthesized by Vinony from 21 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Key facts

Drug.C: 18
Drug.H: 21
Drug.N: 1
Drug.O: 4
Drug.verifiedrevid: 464196835
Drug.image: Oxycodone.svg
Drug.image_class: skin-invert-image
Drug.width: 183
Drug.image2: Oxycodone molecule ball.png
Drug.image_class2: bg-transparent
Drug.width2: 225
Drug.tradename: Roxicodone, OxyContin, Endone, others
Drug.MedlinePlus: a682132
Drug.DailyMedID: Oxycodone
Drug.pregnancy_AU: C
Drug.dependency_liability: High
Drug.addiction_liability: High
Drug.routes_of_administration: By mouth, sublingual, intramuscular, intravenous, intranasal, subcutaneous, transdermal, rectal, epidural

via Wikipedia infobox

Chemical data

Formula: C18H21NO4
Molecular weight: 315.4 g/mol
IUPAC name: (4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
SMILES: CN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)OC)O4)O
InChIKey: BRUQQQPBMZOVGD-XFKAJCMBSA-N
XLogP: 1.2
Polar surface area: 59 Å²
H-bond donors: 1
H-bond acceptors: 5
Formal charge: 0

via PubChem

Research

6,111 papers

via PubMed

Article · Русский

Оксикодон (перкоцет, перкосет) — обезболивающий препарат, полусинтетический опиоид, получаемый из тебаина. Разработан в 1916 году в Германии. Являлся одним из нескольких новых полусинтетических опиоидов, созданных в попытке улучшить существующие опиоиды: морфин, диацетилморфин (героин) и кодеин. Оксикодон обычно выписывается для облегчения умеренной или сильной боли.

Abstract from DBpedia / Wikipedia · CC BY-SA