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pappalysin-1
Sign in to saveAlso known as EC 3.4.24.79, PAPPA, IPR030433
Pappalysin-1, also known as pregnancy-associated plasma protein A, and insulin-like growth factor binding protein-4 protease is a protein encoded by the PAPPA gene in humans. PAPPA is a secreted protease whose main substrate is insulin-like growth factor binding proteins. Pappalysin-1 is also used in screening tests for Down syndrome.
Wikidata facts
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- EC enzyme number
- 3.4.24.79
via Wikidata · CC0
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Encyclopedic overview
3 sectionsContents
- Function
- Interactions
- References
Pappalysin-1, also known as pregnancy-associated plasma protein A, and insulin-like growth factor binding protein-4 protease is a protein encoded by the PAPPA gene in humans. PAPPA is a secreted protease whose main substrate is insulin-like growth factor binding proteins. Pappalysin-1 is also used in screening tests for Down syndrome.
== Function ==
Excerpted from Wikipedia’s “pappalysin-1” article, available under the CC BY-SA 4.0 licence.