English
Structure via PubChem · Public domain (PubChem)
pazinaclone
Sign in to savePazinaclone (DN-2327) is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs. Some other cyclopyrrolone drugs include zopiclone and eszopiclone.
Chemical data
- Formula
- C25H23ClN4O4
- Molecular weight
- 478.9 g/mol
- IUPAC name
- 2-(7-chloro-1,8-naphthyridin-2-yl)-3-[2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-oxoethyl]-3H-isoindol-1-one
- SMILES
- C1CN(CCC12OCCO2)C(=O)CC3C4=CC=CC=C4C(=O)N3C5=NC6=C(C=C5)C=CC(=N6)Cl
- InChIKey
- DPGKFACWOCLTCA-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 84.9 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 478.141
Show 3 more facts
- chemical formula
- C₂₅H₂₃ClN₄O₄
- canonical SMILES
- C1CN(CCC12OCCO2)C(=O)CC3C4=CC=CC=C4C(=O)N3C5=NC6=C(C=C5)C=CC(=N6)Cl
- Commons category
- Pazinaclone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Pazinaclone (DN-2327) is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs. Some other cyclopyrrolone drugs include zopiclone and eszopiclone.
Pazinaclone has a very similar pharmacological profile to the benzodiazepines including sedative and anxiolytic properties, but with less amnestic effects, and at low doses it is a relatively selective anxiolytic, with sedative effects only appearing at higher doses.
Excerpted from Wikipedia’s “pazinaclone” article, available under the CC BY-SA 4.0 licence.