PBRM1
Sign in to saveAlso known as BAF180, PB1, polybromo 1, SMARCH1, RCC
Protein polybromo-1 (PB1) also known as BRG1-associated factor 180 (BAF180) is a protein that in humans is encoded by the PBRM1 gene.
In the Vinony graph
Vinony's link graph records 5 inbound references to PBRM1, and connects out to PubMed, Ensembl genome database project and protein.
It is catalogued under the topic Genes on human chromosome 3.
Vinony links it to 6 Wikipedia language editions.
Gene data
PBRM1- Name
- polybromo 1
- Type
- protein-coding
- Position
- 52,544,271–52,685,979 (−)
- Aliases
- BAF180, PB1, RCC, SMARCH1
- Ensembl
- ENSG00000163939
- RefSeq RNA
- NM_001350074.2, NM_001350075.2, NM_001350076.2, NM_001350077.2, NM_001350078.2
- RefSeq protein
- NP_001337003.1, NP_001337004.1, NP_001337005.1, NP_001337006.1, NP_001337007.1
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
polybromo 1
- Symbol
- PBRM1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:52,544,271-52,685,979
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 10044
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55193
- genomic end
- 52719933
- genomic start
- 52579368
- chromosome
- human chromosome 3
- cytogenetic location
- 3p21.1
- expressed in
- germinal epithelium
Sources (4)
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Structure and function
- Clinical significance
- Role in renal carcinoma
- References
- Further reading
Protein polybromo-1 (PB1) also known as BRG1-associated factor 180 (BAF180) is a protein that in humans is encoded by the PBRM1 gene.
== Structure and function ==
Excerpted from Wikipedia’s “PBRM1” article, available under the CC BY-SA 4.0 licence.