PBRM1
Sign in to saveAlso known as BAF180, PB1, polybromo 1, SMARCH1, RCC
Protein polybromo-1 (PB1) also known as BRG1-associated factor 180 (BAF180) is a protein that in humans is encoded by the PBRM1 gene.
Gene data
PBRM1- Name
- polybromo 1
- Type
- protein-coding
- Aliases
- BAF180, PB1, RCC, SMARCH1
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012].
via MyGene.info
Gene · Ensembl
polybromo 1
- Symbol
- PBRM1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:52,544,271-52,685,979
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 10044
- exact match
- identifiers.org/ncbigene/55193
- genomic end
- 52719933
- genomic start
- 52579368
- cytogenetic location
- 3p21.1
Sources (4)
via Wikidata · CC0
~2 min read
Article
5 sectionsContents
- Structure and function
- Clinical significance
- Role in renal carcinoma
- References
- Further reading
Protein polybromo-1 (PB1) also known as BRG1-associated factor 180 (BAF180) is a protein that in humans is encoded by the PBRM1 gene.
== Structure and function ==