PDE4A
Sign in to saveAlso known as DPDE2, PDE4, PDE46, phosphodiesterase 4A
'''cAMP-specific 3',5'-cyclic phosphodiesterase 4A' is an enzyme that in humans is encoded by the PDE4A'' gene.
Gene data
PDE4A- Name
- phosphodiesterase 4A
- Type
- protein-coding
- Aliases
- DPDE2, PDE4, PDE46
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
via MyGene.info
Wikidata facts
- Image
- Protein PDE4A PDB 1loi.png
Show 5 more facts
- HomoloGene ID
- 4520
- exact match
- identifiers.org/ncbigene/5141
- genomic end
- 10469630
- genomic start
- 10527449
- cytogenetic location
- 19p13.2
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
'''cAMP-specific 3',5'-cyclic phosphodiesterase 4A' is an enzyme that in humans is encoded by the PDE4A'' gene.
== Function ==