PELI1
Sign in to saveAlso known as pellino E3 ubiquitin protein ligase 1
Protein pellino homolog 1 is a protein that in humans is encoded by the PELI1 gene.
Gene data
PELI1- Name
- pellino E3 ubiquitin protein ligase 1
- Type
- protein-coding
- Position
- 64,092,652–64,144,420 (−)
- Ensembl
- ENSG00000197329
- RefSeq RNA
- NM_020651.4, XM_011532994.4, XM_011532997.3, XM_017004520.2, XM_047445137.1
- RefSeq protein
- NP_065702.2, XP_011531296.1, XP_011531299.1, XP_016860009.1, XP_047301093.1
Enables ubiquitin protein ligase activity. Involved in several processes, including negative regulation of necroptotic process; protein polyubiquitination; and response to lipopolysaccharide. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
protein polyubiquitinationprotein polyubiquitinationregulation of Toll signaling pathwayprotein ubiquitinationresponse to lipopolysaccharidepositive regulation of canonical NF-kappaB signal transductionproteasome-mediated ubiquitin-dependent protein catabolic processregulation of necroptotic process
Molecular function
Pathways
Cytokine Signaling in Immune systemToll Like Receptor 4 (TLR4) CascadeMyD88:MAL(TIRAP) cascade initiated on plasma membraneToll Like Receptor 9 (TLR9) CascadeToll Like Receptor 10 (TLR10) CascadeToll Like Receptor 5 (TLR5) CascadeToll Like Receptor TLR1:TLR2 CascadeToll Like Receptor 7/8 (TLR7/8) CascadeToll Like Receptor TLR6:TLR2 CascadeInnate Immune System
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 23243
- genomic start
- 64092652
- exact match
- identifiers.org/ncbigene/57162
- genomic end
- 64144420
- cytogenetic location
- 2p14
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Protein pellino homolog 1 is a protein that in humans is encoded by the PELI1 gene.
==References==
Connections
Q180686
Entity
human chromosome 2
Entity
Ensembl genome database project
Entity
protein
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
Entity
bibcode
Entity
human genome
Entity
Q229883
Entity
base pair
Entity
locus
Entity
gene expression
Entity
Online Mendelian Inheritance in Man
Entity
Q22908627
Entity
Entrez
Entity
Q905695
Entity
Gene Ontology
Entity
GeneCards
Entity