پمترکسید

Key facts

Drug.Verifiedfields

changed

Drug.verifiedrevid

464197624

Drug.image

Pemetrexed.svg

Drug.image_class

skin-invert-image

Drug.image2

Pemetrexed ball-and-stick.png

Drug.image_class2

bg-transparent

Drug.tradename

Alimta, Pemfexy, Ciambra, others

Drug.DailyMedID

Pemetrexed

Drug.pregnancy_AU

D

Drug.routes_of_administration

Intravenous

Drug.ATC_prefix

L01

Drug.ATC_suffix

BA04

Drug.legal_AU

S4

Drug.legal_UK

POM

Drug.legal_US

Rx-only

Drug.legal_EU

Rx-only

Drug.bioavailability

NA

Drug.protein_bound

81%

via Wikipedia infobox

Chemical data

Formula

C20H21N5O6

Molecular weight

427.4 g/mol

IUPAC name

(2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

SMILES

C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O

InChIKey

WBXPDJSOTKVWSJ-ZDUSSCGKSA-N

XLogP

0.2

Polar surface area

187 Ų

H-bond donors

6

H-bond acceptors

6

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

2004

Admin. routes

parenteral

Indications

neoplasm, non-small cell lung carcinoma, gastric carcinoma, head and neck squamous cell carcinoma

via ChEMBL · EBI

Wikidata facts

Mass

427.149183

Has use

medication

via Wikidata · CC0