Structure via PubChem · Public domain (PubChem)
tenoxicam
Sign in to saveAlso known as Ro-120068000, Ténoxicam, Tenoxicamum
Tenoxicam, sold under the brand name Mobiflex among others, is a nonsteroidal anti-inflammatory drug (NSAID). It is used to relieve inflammation, swelling, stiffness, and pain associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis (a type of arthritis involving the spine), tendinitis (inflammation of a tendon), bursitis (inflammation of a bursa, a fluid-filled sac located around joints and near the bones), and periarthritis of the shoulders or hips (inflammation of tissues surrounding these joints).
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443408783
- Drug.IUPAC_name
- 4-hydroxy-2-methyl-N-(pyridin-2-yl)-1λ6-thieno[2,3-e][1,2]thiazine-3-carboxamide-1,1-dioxide
- Drug.image
- Tenoxicam FormulaV1.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Mobiflex, Tilcotil, others
- Drug.legal_AU
- S4
- Drug.legal_UK
- POM
- Drug.routes_of_administration
- Oral
- Drug.protein_bound
- High
- Drug.elimination_half life
- 30–140 hours
- Drug.CAS_number
- 59804-37-4
- Drug.ATC_prefix
- M01
- Drug.ATC_suffix
- AC02
- Drug.PubChem
- 5282194
- Drug.DrugBank
- DB00469
- Drug.ChEBI
- 32192
via Wikipedia infobox
Chemical data
- Formula
- C13H11N3O4S2
- Molecular weight
- 337.4 g/mol
- IUPAC name
- 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide
- SMILES
- CN1C(=C(C2=C(S1(=O)=O)C=CS2)O)C(=O)NC3=CC=CC=N3
- InChIKey
- LZNWYQJJBLGYLT-UHFFFAOYSA-N
- XLogP
- 1.1
- Polar surface area
- 136 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Research
698 papers- Tenoxicam and renal function.Drug safety · 1995
- Clinical pharmacokinetics of tenoxicam.Clinical pharmacokinetics · 1994
- Tenoxicam loaded hyalcubosomes for osteoarthritis.International journal of pharmaceutics · 2021
- Single dose oral tenoxicam for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2009
- Tenoxicam. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.Drugs · 1987
via PubMed
~4 min read
Encyclopedic overview
8 sectionsContents
- Contraindications
- Pregnancy and breastfeeding
- Interactions
- Mechanism of action
- Society and culture
- Research
- See also
- References
Tenoxicam, sold under the brand name Mobiflex among others, is a nonsteroidal anti-inflammatory drug (NSAID). It is used to relieve inflammation, swelling, stiffness, and pain associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis (a type of arthritis involving the spine), tendinitis (inflammation of a tendon), bursitis (inflammation of a bursa, a fluid-filled sac located around joints and near the bones), and periarthritis of the shoulders or hips (inflammation of tissues surrounding these joints).
Tenoxicam belongs to the class of NSAIDs known as oxicams.
Excerpted from Wikipedia’s “tenoxicam” article, available under the CC BY-SA 4.0 licence.