PFDN5
Sign in to saveAlso known as MM-1, MM1, PFD5, prefoldin subunit 5
Prefoldin subunit 5 is a protein that in humans is encoded by the PFDN5 gene.
In the Vinony graph
Within Vinony's link graph, PFDN5 is referenced by 4 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Its subject is documented across 5 Wikipedia language editions.
Gene data
PFDN5- Name
- prefoldin subunit 5
- Type
- protein-coding
- Position
- 53,295,291–53,299,455 (+)
- Aliases
- MM-1, MM1, PFD5
- Ensembl
- ENSG00000291834
- RefSeq RNA
- NM_002624.4, NM_145896.2, NM_145897.3
- RefSeq protein
- NP_002615.2, NP_665904.1
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
prefoldin subunit 5
- Symbol
- PFDN5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:53,295,291-53,299,455
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 1972
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5204
- genomic end
- 53299452
- genomic start
- 53689075
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.13
- expressed in
- substantia nigra
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Prefoldin subunit 5 is a protein that in humans is encoded by the PFDN5 gene.
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
Excerpted from Wikipedia’s “PFDN5” article, available under the CC BY-SA 4.0 licence.