Phosphofructokinase, platelet
Sign in to saveAlso known as PFK-C, 6-phosphofructokinase, platelet type, phosphohexokinase, 6-phosphofructokinase type C, PFKP, phosphofructo-1-kinase isozyme C, ATP-dependent 6-phosphofructokinase, platelet type, phosphofructokinase 1
Phosphofructokinase, platelet, also known as PFKP is an enzyme which in humans is encoded by the PFKP gene.
In the Vinony graph
Within Vinony's link graph, Phosphofructokinase, platelet is referenced by 474 other articles, and connects out to PubMed, human chromosome 10 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 10.
Its subject is documented across 6 Wikipedia language editions.
Protein · UniProt
ATP-dependent 6-phosphofructokinase, platelet type
- Gene
- PFKP
- Organism
- Homo sapiens (Human)
- Length
- 784 aa
- Molecular mass
- 85,596 Da
- Evidence
- 1: Evidence at protein level
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
Swiss-Prot (reviewed) · via UniProt
Research
201 papers- Mutual regulation between phosphofructokinase 1 platelet isoform and VEGF promotes glioblastoma tumor growth.Cell death & disease · 2022
- Platelet isoform of phosphofructokinase accelerates malignant features in breast cancer.Oncology reports · 2022
- Phosphofructokinase Platelet Overexpression Accelerated Colorectal Cancer Cell Growth and Motility.Journal of Cancer · 2023
- Selective activation of PFKL suppresses the phagocytic oxidative burst.Cell · 2021
- Phosphofructokinase 1 platelet isoform induces PD-L1 expression to promote glioblastoma immune evasion.Genes & genomics · 2022
via PubMed
Wikidata facts
- Instance of
- protein
Show 2 more facts
- cell component
- extracellular exosome
- found in taxon
- Homo sapiens
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactive pathway map
- References
- Further reading
- External links
Phosphofructokinase, platelet, also known as PFKP is an enzyme which in humans is encoded by the PFKP gene.
== Function ==
Excerpted from Wikipedia’s “Phosphofructokinase, platelet” article, available under the CC BY-SA 4.0 licence.