PIK3R1

Name

phosphoinositide-3-kinase regulatory subunit 1

Type

protein-coding

Position

68,215,740–68,301,821 (+)

Aliases

AGM7, GRB1, IMD36, p85, p85-ALPHA, p85alpha

Ensembl

ENSG00000145675

RefSeq RNA

NM_001242466.2, NM_001445921.1, NM_001445922.1, NM_001445923.1, NM_181504.4

RefSeq protein

NP_001229395.1, NP_001432850.1, NP_001432851.1, NP_001432852.1, NP_852556.2

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011].

via MyGene.info

Gene · Ensembl

phosphoinositide-3-kinase regulatory subunit 1

Symbol

PIK3R1

Biotype

Protein coding

Organism

Homo sapiens

Location

5:68,215,740-68,301,821

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein PIK3R1 PDB 1bfi.png

via Wikidata · CC0