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Structure via PubChem · Public domain (PubChem)
piperidione
Sign in to saveAlso known as 3,3-Diethyl-2,4-dioxopiperidine
Piperidione (trade name Sedulon) is a sedative drug, structurally related to methyprylon and pyrithyldione. It used to be marketed by Roche as a cough medicine available in liquid form. In the US, it was approved by the FDA on grounds of safety alone in 1947. After Roche failed to submit evidence of efficacy to the Drug Efficacy Study Implementation program in 1972, it was withdrawn from the US market.
Chemical data
- Formula
- C9H15NO2
- Molecular weight
- 169.22 g/mol
- IUPAC name
- 3,3-diethylpiperidine-2,4-dione
- SMILES
- CCC1(C(=O)CCNC1=O)CC
- InChIKey
- RGEVWUKXWFOAID-UHFFFAOYSA-N
- XLogP
- 0.8
- Polar surface area
- 46.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
- Indications
- Cough
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 169.11
Show 4 more facts
- chemical formula
- C₉H₁₅NO₂
- canonical SMILES
- CCC1(C(=O)CCNC1=O)CC
- has characteristic
- bitterness
- Commons category
- Piperidione
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Piperidione (trade name Sedulon) is a sedative drug, structurally related to methyprylon and pyrithyldione. It used to be marketed by Roche as a cough medicine available in liquid form. In the US, it was approved by the FDA on grounds of safety alone in 1947. After Roche failed to submit evidence of efficacy to the Drug Efficacy Study Implementation program in 1972, it was withdrawn from the US market.
== See also == Glutethimide
Excerpted from Wikipedia’s “piperidione” article, available under the CC BY-SA 4.0 licence.