PKP4

Name

plakophilin 4

Type

protein-coding

Position

158,456,900–158,682,879 (+)

Aliases

p0071

Ensembl

ENSG00000144283

RefSeq RNA

NM_001005476.4, NM_001304969.3, NM_001304970.3, NM_001304971.2, NM_001377218.1

RefSeq protein

NP_001005476.1, NP_001291898.1, NP_001291899.1, NP_001291900.1, NP_001364147.1

Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015].

via MyGene.info

Gene · Ensembl

plakophilin 4

Symbol

PKP4

Biotype

Protein coding

Organism

Homo sapiens

Location

2:158,456,895-158,682,955

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0