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GeneQ18030324· pop 5· linked from 486 articles

P2RY4

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Also known as NRU, P2P, P2Y4, UNR, pyrimidinergic receptor P2Y4

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.

Gene data

P2RY4
Name
pyrimidinergic receptor P2Y4
Type
protein-coding
Chromosome
X
Position
70,258,166–70,260,204 (−)
Aliases
NRU, P2P, P2Y4, UNR
Ensembl
ENSG00000186912
RefSeq RNA
NM_002565.4
RefSeq protein
NP_002556.1

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

Neuroactive ligand-receptor interaction - Homo sapiens (human)Taste transduction - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)GPCR downstream signallingP2Y receptorsNucleotide-like (purinergic) receptorsG alpha (i) signalling eventsGPCR ligand binding

via MyGene.info

Gene · Ensembl

pyrimidinergic receptor P2Y4

Symbol
P2RY4
Biotype
Protein coding
Organism
Homo sapiens
Location
Chr X:70,258,166-70,260,204
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
20568
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/5030
chromosome
human X chromosome
genomic end
70260204
genomic start
70258166
cytogenetic location
Xq13.1
expressed in
transverse colon
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
Contents
  • See also
  • References
  • Further reading
  • External links

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.

The product of this gene, P2Y4, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.

Excerpted from Wikipedia’s “P2RY4” article, available under the CC BY-SA 4.0 licence.

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via Wikidata sitelinks · CC0