PI4KA
Sign in to saveAlso known as PI4K-ALPHA, PIK4CA, pi4K230, PMGYCHA, phosphatidylinositol 4-kinase alpha, SPG84, GIDID2
Phosphatidylinositol 4-kinase alpha is an enzyme that in humans is encoded by the PI4KA gene.
In the Vinony graph
Within Vinony's link graph, PI4KA is referenced by 6 other articles, and connects out to PubMed, Ensembl genome database project and nitrogen.
It sits within the topics EC 2.7.1 and Genes on human chromosome 22.
Its subject is documented across 5 Wikipedia language editions.
Gene data
PI4KA- Name
- phosphatidylinositol 4-kinase alpha
- Type
- protein-coding
- Position
- 20,707,691–20,859,417 (−)
- Aliases
- GIDID2, PI4K-ALPHA, PIK4CA, PMGYCHA, SPG84, pi4K230
- Ensembl
- ENSG00000241973
- RefSeq RNA
- NM_001362862.2, NM_001362863.2, NM_002650.2, NM_058004.4, XM_005261635.2
- RefSeq protein
- NP_001349791.1, NP_001349792.1, NP_477352.3, XP_005261692.1, XP_011528528.1
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2018].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
phosphatidylinositol 4-kinase alpha
- Symbol
- PI4KA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:20,707,691-20,859,417
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 11171
- genomic start
- 21061979
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5297
- genomic end
- 21213705
- chromosome
- human chromosome 22
- cytogenetic location
- 22q11.21
- expressed in
- putamen
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Phosphatidylinositol 4-kinase alpha is an enzyme that in humans is encoded by the PI4KA gene.
== Function ==
Excerpted from Wikipedia’s “PI4KA” article, available under the CC BY-SA 4.0 licence.