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plazomicin

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Plazomicin, sold under the brand name Zemdri, is an aminoglycoside antibiotic used to treat complicated urinary tract infections. As of 2019 it is recommended only for those in whom alternatives are not an option. It is given by injection into a vein.

Key facts

Drug.image
Plazomicin structure.svg
Drug.image_class
skin-invert-image
Drug.pronounce
pla" zoe mye' sin
Drug.tradename
Zemdri
Drug.MedlinePlus
a618037
Drug.DailyMedID
Plazomicin
Drug.routes_of_administration
Intravenous
Drug.class
Aminoglycoside
Drug.ATC_prefix
J01
Drug.ATC_suffix
GB14
Drug.legal_US
Rx-only
Drug.index2_label
as salt
Drug.CAS_number
1154757-24-0
Drug.PubChem
42613186
Drug.DrugBank
DB12615
Drug.ChemSpiderID
26390008
Drug.UNII
LYO9XZ250J
Drug.KEGG
D10151

via Wikipedia infobox

~3 min read

Encyclopedic overview

6 sections
Contents
  • Medical uses
  • History
  • Synthesis
  • Names
  • References
  • Further reading

Plazomicin, sold under the brand name Zemdri, is an aminoglycoside antibiotic used to treat complicated urinary tract infections. As of 2019 it is recommended only for those in whom alternatives are not an option. It is given by injection into a vein.

Common side effects include kidney problems, diarrhea, nausea, and blood pressure changes. Other severe side effects include hearing loss, Clostridioides difficile-associated diarrhea, anaphylaxis, and muscle weakness. Use during pregnancy may harm the baby. Plazomicin works by decreasing the ability of bacteria to make protein.

Excerpted from Wikipedia’s “plazomicin” article, available under the CC BY-SA 4.0 licence.