polymyxins
Sign in to saveclass=skin-invert-image|thumb|Colistin class=skin-invert-image|thumb|Polymyxin B (R=H is polymyxin B2, R=CH3 is polymyxin B1) Polymyxins are antibiotics. Polymyxins B and E (also known as colistin) are used in the treatment of Gram-negative bacterial infections. They work mostly by breaking up the bacterial cell membrane. They are part of a broader class of molecules called nonribosomal peptides.
Article
8 sectionsContents
- Medical use
- Mechanism of action
- Chemistry
- Biosynthesis
- Research
- Compound mixtures in Polymyxin B drug
- See also
- References
class=skin-invert-image|thumb|Colistin class=skin-invert-image|thumb|Polymyxin B (R=H is polymyxin B2, R=CH3 is polymyxin B1) Polymyxins are antibiotics. Polymyxins B and E (also known as colistin) are used in the treatment of Gram-negative bacterial infections. They work mostly by breaking up the bacterial cell membrane. They are part of a broader class of molecules called nonribosomal peptides.
They are produced in nature by Gram-positive bacteria such as Paenibacillus polymyxa.