Probucol, sold under the trade name Lorelco among others, is an lipid-lowering agent initially developed for the treatment of coronary artery disease. Clinical use was discontinued in some countries after it was found that the drug may have the undesired effect of lowering HDL-C in patients with a previous history of heart disease. It may also cause QT interval prolongation.
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{{Infobox drug | Verifiedfields = changed | verifiedrevid = 464214831 | IUPAC_name = 4,4'-[Propane-2,2-diylbis(thio)]bis(2,6-di-tert-butylphenol) | image = Probucol.svg | image_class = skin-invert-image
| pronounce = | tradename = Lorelco | Drugs.com = | MedlinePlus = a611037 | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
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