Structure via PubChem · Public domain (PubChem)
ciprofibrate
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Ciprofibrate is a fibrate that was developed as a lipid-lowering agent.
Chemical data
- Formula
- C13H14Cl2O3
- Molecular weight
- 289.15 g/mol
- IUPAC name
- 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
- SMILES
- CC(C)(C(=O)O)OC1=CC=C(C=C1)C2CC2(Cl)Cl
- InChIKey
- KPSRODZRAIWAKH-UHFFFAOYSA-N
- XLogP
- 3.4
- Polar surface area
- 46.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1985
- Admin. routes
- oral
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
564 papers- Ciprofibrate--a profile.Postgraduate medical journal · 1993
- Ciprofibrate attenuates airway remodeling in cigarette smoke-exposed rats.Respiratory physiology & neurobiology · 2020
- A new ciprofibrate calcium salt with improved solubility and intrinsic dissolution rate.Journal of pharmaceutical sciences · 2024
- Efficacy and safety of ciprofibrate in hyperlipoproteinaemias.Atherosclerosis · 1996
- Ciprofibrate regulation of rat hepatic bilirubin glucuronidation and UDP-glucuronosyltransferases expression.European journal of drug metabolism and pharmacokinetics · 2012
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 288.032
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₃H₁₄Cl₂O₃
- canonical SMILES
- CC(C)(C(=O)O)OC1=CC=C(C=C1)C2CC2(Cl)Cl
- World Health Organisation international non-proprietary name
- ciprofibrate
- significant drug interaction
- pravastatin
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Ciprofibrate is a fibrate that was developed as a lipid-lowering agent.
It was patented in 1972 and approved for medical use in 1985.
Excerpted from Wikipedia’s “ciprofibrate” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0