etofibrate
Sign in to saveEtofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.
Research
93 papers- Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2001
- Studies with etofibrate in the rat. Part I: Effects on glycerol, free fatty acid and triacylglycerol metabolism.Biochimica et biophysica acta · 1988
- [Efficacy and safety of etofibrate in patients with non-proliferative diabetic retinopathy].Klinische Monatsblatter fur Augenheilkunde · 2009
- Confirmation of efficacy of etofibrate against peripheral atherosclerosis in non-human primates which model human lesion types I-VII.Arzneimittel-Forschung · 1996
- Biliary lipids, lithogenic index and biliary drug concentrations during etofibrate and bezafibrate treatment.European journal of drug metabolism and pharmacokinetics · 1995
via PubMed
Wikidata facts
- Mass
- 363.08735
Show 4 more facts
- chemical formula
- C₁₈H₁₈ClNO₅
- canonical SMILES
- CC(C)(C(=O)OCCOC(=O)C1=CN=CC=C1)OC2=CC=C(C=C2)Cl
- World Health Organisation international non-proprietary name
- etofibrate
- Commons category
- Etofibrate
Sources (2)
via Wikidata · CC0
~1 min read
Article
1 sectionsContents
- References
Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.
==References==
Available in 11 languages
via Wikidata sitelinks · CC0
Connections
nicotinic acid
Entity
GW-501516
Entity
liver
Entity
medication
Entity
circulatory system
Entity
blood vessel
Entity
digital object identifier
Entity
chemical formula
Entity
ester
Entity
ibuprofen
Entity
molar mass
Entity
hydrolysis
Entity
Q180686
Entity
dietary fiber
Entity
CAS Registry Number
Entity
PubChem
Entity
gastrointestinal tract
Entity
Anatomical Therapeutic Chemical Classification System
Entity
pharmacokinetics
Entity
cannabidiol
Entity