etofibrate
Sign in to saveEtofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.
Research
93 papers- Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2001
- Studies with etofibrate in the rat. Part I: Effects on glycerol, free fatty acid and triacylglycerol metabolism.Biochimica et biophysica acta · 1988
- [Efficacy and safety of etofibrate in patients with non-proliferative diabetic retinopathy].Klinische Monatsblatter fur Augenheilkunde · 2009
- Confirmation of efficacy of etofibrate against peripheral atherosclerosis in non-human primates which model human lesion types I-VII.Arzneimittel-Forschung · 1996
- Biliary lipids, lithogenic index and biliary drug concentrations during etofibrate and bezafibrate treatment.European journal of drug metabolism and pharmacokinetics · 1995
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 363.08735
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₈H₁₈ClNO₅
- canonical SMILES
- CC(C)(C(=O)OCCOC(=O)C1=CN=CC=C1)OC2=CC=C(C=C2)Cl
- World Health Organisation international non-proprietary name
- etofibrate
- Commons category
- Etofibrate
Sources (2)
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Encyclopedic overview
1 sectionsContents
- References
Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.
==References==
Excerpted from Wikipedia’s “etofibrate” article, available under the CC BY-SA 4.0 licence.
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