Pur-alpha is a protein that in humans is encoded by the PURA gene located at chromosome 5, band q31.
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008].
via MyGene.info
Pur-alpha is a protein that in humans is encoded by the PURA gene located at chromosome 5, band q31.
Pur-alpha is an ancient, multi-functional DNA- and RNA-binding protein. PURA is expressed in every human tissue, where it exists as a protein of 322 amino acids. According to convention, PURA, the gene, is written italicized in all upper case letters. Pur-alpha, the protein, is written with the first letter capitalized and can be found listed as Pur-alpha, Pur-α, Pura, Puralpha, Pur alpha and Pur1.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).