File:Ranitidine.svg · Wikimedia Commons · See Wikimedia Commons
ranitidine
Sign in to saveAlso known as RAN
Ranitidine, sold under the brand name Zantac among others, is a medication used to decrease stomach acid production. It is used in the treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. It can be given by mouth, injection into a muscle, or injection into a vein.
OverviewAI-generated
Ranitidine is a chemical compound with the formula C₁₃H₂₂N₄O₃S. Its IUPAC name is 1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine. The substance has a mass of 314.141 and a weight of 314.41. It possesses a charge of 0, an xlogp of 0.3, and a tpsa of 112. The molecule contains two hydrogen bond donors and seven hydrogen bond acceptors.
The canonical SMILES notation for ranitidine is CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C. It is also identified by the InChIKey VMXUWOKSQNHOCA-UHFFFAOYSA-N. The stylized name for the compound is raNITIdine.
Ranitidine is referenced by 583 other encyclopedia articles. A search on PubMed yields 7594 results for the query "ranitidine". The compound is associated with the Commons category "Ranitidine" and has a PubChem CID of 5039.
Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.StdInChIKey
- VMXUWOKSQNHOCA-UHFFFAOYSA-N
- Drug.image
- Ranitidine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250
- Drug.image2
- File:Ranitidine-A-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.JAN
- ranitidine hydrochloride
- Drug.tradename
- Zantac, others
- Drug.MedlinePlus
- a601106
- Drug.DailyMedID
- Ranitidine
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- By mouth, intravenous (IV)
- Drug.class
- Histamine H2 receptor antagonist, aka H2 blocker
- Drug.ATC_prefix
- A02
- Drug.ATC_suffix
- BA02
- Drug.ATC_supplemental
- (ranitidine bismuth citrate)
- Drug.legal_AU
- S4
- Drug.legal_AU_comment
- / S2 (Pharmacy Medicine)
via Wikipedia infobox
Chemical data
- Formula
- C13H22N4O3S
- Molecular weight
- 314.41 g/mol
- IUPAC name
- 1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
- SMILES
- CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C
- InChIKey
- VMXUWOKSQNHOCA-UHFFFAOYSA-N
- XLogP
- 0.3
- Polar surface area
- 112 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Research
7,594 papers- Ranitidine hydrochloride.Drug intelligence & clinical pharmacy · 1983
- Ranitidine: a new H2-receptor antagonist.The New England journal of medicine · 1983
- Clinical pharmacokinetics of ranitidine.Clinical pharmacokinetics · 1984
- Ranitidine.JAMA · 1983
- N-nitrosodimethylamine (NDMA) contamination of ranitidine products: A review of recent findings.Journal of food and drug analysis · 2021
via PubMed
~23 min read
Encyclopedic overview
25 sectionsContents
- Medical uses
- Adverse effects
- Central nervous system
- Cardiovascular
- Gastrointestinal
- Liver
- Lungs
- Blood
- Skin
- Precautions
- Disease-related concerns
- Children
- Drug tests
- <span class="anchor" id="impurities"></span>Cancer-causing due to inherent instability
- List of recalls
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Elderly
- Children
- History
- Preparations
- References
- Notes
- External links
{{Infobox drug | image = Ranitidine.svg | image_class = skin-invert-image | width = 250 | alt = | image2 = File:Ranitidine-A-3D-balls.png | image_class2 = bg-transparent | alt2 = | JAN = ranitidine hydrochloride
| pronounce = | tradename = Zantac, others | Drugs.com = | MedlinePlus = a601106 | DailyMedID = Ranitidine | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth, intravenous (IV) | class = Histamine H2 receptor antagonist, aka H2 blocker | ATC_prefix = A02 | ATC_suffix = BA02 | ATC_supplemental = (ranitidine bismuth citrate)
Excerpted from Wikipedia’s “ranitidine” article, available under the CC BY-SA 4.0 licence.