imipraminoxide
Sign in to saveImipraminoxide (brand names Imiprex, Elepsin), or 'imipramine N-oxide', is a tricyclic antidepressant (TCA) that was introduced in Europe in the 1960s for the treatment of depression.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 296.189
Show 3 more facts
- chemical formula
- C₁₉H₂₄N₂O
- canonical SMILES
- C[N+](C)(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)[O-]
- Commons category
- Imipraminoxide
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Encyclopedic overview
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Imipraminoxide (brand names Imiprex, Elepsin), or 'imipramine N-oxide', is a tricyclic antidepressant (TCA) that was introduced in Europe in the 1960s for the treatment of depression.
Imipraminoxide is both an analogue and a metabolite of imipramine, and has similar effects. However, in clinical trials, imipraminoxide was found to have a faster onset of action, slightly higher efficacy, and fewer and less marked side effects, including diminished orthostatic hypotension and anticholinergic effects like dry mouth, sweating, dizziness, and fatigue.
Excerpted from Wikipedia’s “imipraminoxide” article, available under the CC BY-SA 4.0 licence.