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Nitroxazepine
Sign in to saveNitroxazepine (brand name Sintamil) is a tricyclic antidepressant (TCA) which was introduced by Ciba-Geigy (now Novartis) for the treatment of depression in India in 1982. It is also indicated for the treatment of nocturnal enuresis. Nitroxazepine acts as a serotonin-norepinephrine reuptake inhibitor and has similar effects to imipramine, but with certain advantages, such as lower anticholinergic side effects.
In the Vinony graph
Vinony's link graph records 720 inbound references to Nitroxazepine, and connects out to propranolol, N-methylserotonin and atropine.
Vinony files it under Chemical pages without DrugBank identifier, Dibenzoxazepines and Drugs not assigned an ATC code.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C18H19N3O4
- Molecular weight
- 341.4 g/mol
- IUPAC name
- 5-[3-(dimethylamino)propyl]-8-nitrobenzo[b][1,4]benzoxazepin-6-one
- SMILES
- CN(C)CCCN1C2=CC=CC=C2OC3=C(C1=O)C=C(C=C3)[N+](=O)[O-]
- InChIKey
- CGYWLLGTCBIGSR-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 78.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 341.138
Show 3 more facts
- chemical formula
- C₁₈H₁₉N₃O₄
- canonical SMILES
- CN(C)CCCN1C2=CC=CC=C2OC3=C(C1=O)C=C(C=C3)[N+](=O)[O-]
- Commons category
- Nitroxazepine
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Nitroxazepine (brand name Sintamil) is a tricyclic antidepressant (TCA) which was introduced by Ciba-Geigy (now Novartis) for the treatment of depression in India in 1982. It is also indicated for the treatment of nocturnal enuresis. Nitroxazepine acts as a serotonin-norepinephrine reuptake inhibitor and has similar effects to imipramine, but with certain advantages, such as lower anticholinergic side effects.
==References==
Excerpted from Wikipedia’s “Nitroxazepine” article, available under the CC BY-SA 4.0 licence.