Structure via PubChem · Public domain (PubChem)
clocinizine
Sign in to saveClocinizine is a first-generation antihistamine of the diphenylmethylpiperazine class. It is marketed in Spain in combination with phenylpropanolamine under the brand name Senioral.
Chemical data
- Formula
- C26H27ClN2
- Molecular weight
- 403 g/mol
- IUPAC name
- 1-[(4-chlorophenyl)-phenylmethyl]-4-[(E)-3-phenylprop-2-enyl]piperazine
- SMILES
- C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl
- InChIKey
- ZSQANMZWGKYDER-JXMROGBWSA-N
- XLogP
- 6.4
- Polar surface area
- 6.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 402.186
Show 4 more facts
- chemical formula
- C₂₆H₂₇ClN₂
- canonical SMILES
- C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl
- isomeric SMILES
- C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl
- Commons category
- Clocinizine
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Clocinizine is a first-generation antihistamine of the diphenylmethylpiperazine class. It is marketed in Spain in combination with phenylpropanolamine under the brand name Senioral.
==Synthesis== thumb|center|500px|class=skin-invert-image|Synthesis: Patent:
Excerpted from Wikipedia’s “clocinizine” article, available under the CC BY-SA 4.0 licence.