Gene data
RBP4- Name
- retinol binding protein 4
- Type
- protein-coding
- Position
- 93,590,170–93,603,110 (−)
- Aliases
- MCOPCB10, RDCCAS
- Ensembl
- ENSG00000138207
- RefSeq RNA
- NM_001323517.1, NM_001323518.2, NM_006744.4
- RefSeq protein
- NP_001310446.1, NP_001310447.1, NP_006735.2
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
MetabolismDiseaseMetabolism of vitamins and cofactorsVisual phototransductionRetinoid cycle disease eventsThe canonical retinoid cycle in rods (twilight vision)Diseases associated with visual transductionMetabolism of fat-soluble vitaminsRetinoid metabolism disease eventsDiseases of the neuronal system
via MyGene.info
Gene · Ensembl
retinol binding protein 4
- Symbol
- RBP4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:93,590,170-93,603,110
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Retinol binding protein 1RBP.png
Show 9 more facts
- HomoloGene ID
- 4908
- exact match
- identifiers.org/ncbigene/5950
- found in taxon
- Homo sapiens
- genomic end
- 95361501
- genomic start
- 95351444
- chromosome
- human chromosome 10
- cytogenetic location
- 10q23.33
- expressed in
- decidua
- Commons category
- Retinol binding protein IV
via Wikidata · CC0