remdesivir
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Key facts
- Drug.N
- 6
- Drug.image
- Remdesivir.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Remdesivir-from-xtal-Mercury-3D-ball-and-stick-with-bond-orders.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Veklury
- Drug.MedlinePlus
- a620033
- Drug.DailyMedID
- Remdesivir
- Drug.pregnancy_AU
- B2
- Drug.routes_of_administration
- Intravenous
- Drug.class
- Antiviral
- Drug.ATC_prefix
- J05
- Drug.ATC_suffix
- AB16
Article
34 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Activation
- Mechanism of action
- Pharmacokinetics
- Resistance
- Interactions
- Synthesis
- ''In vitro'' experiments
- Manufacturing
- Society and culture
- Legal status
- Australia
- Canada
- Czech Republic
- European Union
- Iran
- Japan
- Mexico
- Singapore
- United States
- Economics
- Names
- Research
- Ebola
- COVID-19
- Hospitalized patients
- Nonhospitalized outpatients
- Remdesivir/baricitinib
- Remdesivir/interferon beta-1a
- Veterinary uses
- References
- External links
{{Infobox drug | image = Remdesivir.svg | image_class = skin-invert-image | width = | alt = | caption = | image2 = Remdesivir-from-xtal-Mercury-3D-ball-and-stick-with-bond-orders.png | image_class2 = bg-transparent | width2 = | alt2 = | pronounce = | tradename = Veklury | Drugs.com = | MedlinePlus = a620033 | DailyMedID = Remdesivir | pregnancy_AU = B2 | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = Intravenous | class = Antiviral | ATC_prefix = J05 | ATC_suffix = AB16 | ATC_supplemental = | legal_AU = S4 | legal_AU_comment = | legal_BR = | legal_BR_comment = | legal_CA = Rx-only | legal_CA_comment = | legal_DE = | legal_DE_comment = | legal_NZ = | legal_NZ_comment = | legal_UK = POM | legal_UK_comment = | legal_US = Rx-only | legal_US_comment = | legal_EU = Rx-only | legal_EU_comment = | legal_UN = | legal_UN_comment = | legal_status = Schedule H | bioavailability = | protein_bound = | metabolism = | metabolites = | onset = | elimination_half-life = | duration_of_action = | excretion = | CAS_number = 1809249-37-3 | CAS_supplemental = | PubChem = 121304016 | IUPHAR_ligand = | DrugBank = DB14761 | ChemSpiderID = 58827832 | UNII = 3QKI37EEHE | KEGG = D11472 | ChEBI = 145994 | ChEMBL = 4065616 | NIAID_ChemDB = | PDB_ligand = | synonyms = GS-5734, RDV
| IUPAC_name = (2S)-2-{(2R,3S,4R,5R)-[5-(4-Aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxy]phenoxy-(S)-phosphorylamino}propionic acid 2-ethyl-butyl ester | C = 27 | H = 35 | N = 6 | O = 8 | P = 1 | SMILES = CCC(COC(=O)[C@@H](NP(=O)(Oc1ccccc1)OC[C@H]1O[C@@]([C@@H]([C@@H]1O)O)(C#N)c1ccc2n1ncnc2N)C)CC | StdInChI = 1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1 | StdInChI_comment = | StdInChIKey = RWWYLEGWBNMMLJ-YSOARWBDSA-N | density = | density_notes = | melting_point = | melting_high = | melting_notes = | boiling_point = | boiling_notes = | solubility = | sol_units = | specific_rotation = }} Remdesivir, sold under the brand name Veklury, is a broad-spectrum antiviral medication developed by the biopharmaceutical company Gilead Sciences. It is administered via injection into a vein. During the COVID19 pandemic, remdesivir was approved or authorized for emergency use to treat COVID19 in numerous countries.