remifentanil
Sign in to saveRemifentanil, marketed under the brand name Ultiva is a potent, short-acting synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anesthetic. Remifentanil is used for sedation as well as combined with other medications for use in general anesthesia. The use of remifentanil has made possible the use of high-dose opioid and low-dose hypnotic anesthesia, due to synergism between remifentanil and various hypnotic drugs and volatile anesthetics.
Research
7,243 papers- Remifentanil-induced hyperalgesia: the current state of affairs.Current opinion in anaesthesiology · 2024
- Remifentanil.Drugs · 1996
- Remifentanil.Current opinion in critical care · 2001
- Remifentanil and the brain.Acta anaesthesiologica Scandinavica · 2008
- [Remifentanil].Der Anaesthesist · 1997
via PubMed
Article
14 sectionsContents
- Medical uses
- Available forms
- Pharmacology
- Pharmacokinetics
- Pharmacodynamics
- Side-effects
- Abuse potential
- Society and culture
- Development and marketing
- Legal status
- Tert-butyl remifentanil
- Veterinary use
- References
- External links
Remifentanil, marketed under the brand name Ultiva is a potent, short-acting synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anesthetic. Remifentanil is used for sedation as well as combined with other medications for use in general anesthesia. The use of remifentanil has made possible the use of high-dose opioid and low-dose hypnotic anesthesia, due to synergism between remifentanil and various hypnotic drugs and volatile anesthetics.
== Medical uses == Remifentanil is used as an opioid analgesic that has a rapid onset and rapid recovery time. It has been used effectively during craniotomies, spinal surgery, cardiac surgery, and gastric bypass surgery. While opioids function similarly, with respect to analgesia, the pharmacokinetics of remifentanil allows for quicker post-operative recovery.