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EntityQ7316645· pop 18· linked from 56 articles

retapamulin

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Also known as SB-275833, {(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl} 2-({(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl}sulfanyl)acetate

Retapamulin is a topical antibiotic developed by GlaxoSmithKline. It is the first drug in the new class of pleuromutilin antibiotics to be approved for human use. It is marketed as an ointment under the brand names Altabax and Altargo.

~3 min read

Encyclopedic overview

7 sections
Contents
  • Indications
  • Pharmacology
  • Mechanism of action
  • Pharmacokinetics
  • Contraindications
  • Adverse reactions
  • References

{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464381219 | IUPAC_name = (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propano-3aH-cyclopenta[8]annulen-8-yl{[(1R,3s,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]sulfanyl}acetate | image = Retapamulin.svg | image_class = skin-invert-image | image2 = Retapamulin 3D sticks.png | image_class2 = bg-transparent

| tradename = Altabax, Altargo | Drugs.com = | MedlinePlus = a607049 | licence_EU = yes | licence_US = Retapamulin | pregnancy_AU = | pregnancy_US = B | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = POM | legal_US = Rx-only | legal_status = | routes_of_administration = Topical (ointment)

Excerpted from Wikipedia’s “retapamulin” article, available under the CC BY-SA 4.0 licence.