Structure via PubChem · Public domain (PubChem)
spectinomycin
Sign in to saveAlso known as Antibiotic 2233WP, SCM, Actinospectacina, Espectinomicina, Spectinomicina, Spectinomycine, Spectinomycinum
Spectinomycin, sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle.
Chemical data
- Formula
- C14H24N2O7
- Molecular weight
- 332.35 g/mol
- IUPAC name
- (1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one
- SMILES
- C[C@@H]1CC(=O)[C@]2([C@@H](O1)O[C@@H]3[C@H]([C@@H]([C@@H]([C@@H]([C@H]3O2)NC)O)NC)O)O
- InChIKey
- UNFWWIHTNXNPBV-WXKVUWSESA-N
- XLogP
- -3.1
- Polar surface area
- 130 Ų
- H-bond donors
- 5
- H-bond acceptors
- 9
- Formal charge
- 0
via PubChem
Research
3,036 papers- Spectinomycin.The Medical clinics of North America · 1982
- Fed-batch bioproduction of spectinomycin.Advances in biochemical engineering/biotechnology · 1998
- Spectinomycin-resistant Neisseria gonorrhoeae.JAMA · 1977
- Chemistry of spectinomycin.The Japanese journal of antibiotics · 1979
- Drugs five years later. Spectinomycin.Annals of internal medicine · 1976
via PubMed
~4 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Side effects
- Mechanism of action
- Biosynthetic mechanism
- Nature
- History
- References
Spectinomycin, sold under the tradename Trobicin among others, is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle.
Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Severe allergic reactions may occasionally occur. It is generally safe to use during pregnancy. It may be used by those who are allergic to penicillin or cephalosporins. It is in the aminocyclitol class of drugs and works by stopping the making of protein by certain bacteria.
Excerpted from Wikipedia’s “spectinomycin” article, available under the CC BY-SA 4.0 licence.