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Structure via PubChem · Public domain (PubChem)
reversine
Sign in to saveAlso known as 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine
Reversine, or 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation.
Chemical data
- Formula
- C21H27N7O
- Molecular weight
- 393.5 g/mol
- IUPAC name
- 6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine
- SMILES
- C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5
- InChIKey
- ZFLJHSQHILSNCM-UHFFFAOYSA-N
- XLogP
- 3.9
- Polar surface area
- 91 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 393.228
Show 2 more facts
- canonical SMILES
- C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5
- chemical formula
- C₂₁H₂₇N₇O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Reversine, or 2-(4-morpholinoanilino)-6-cyclohexylaminopurine, is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation.
It also has the potential to selectively induce cell death in cancer cells.
Excerpted from Wikipedia’s “reversine” article, available under the CC BY-SA 4.0 licence.