File:Inositol.svg · Wikimedia Commons · See Wikimedia Commons
inositol
Sign in to saveAlso known as 1,2,3,4,5,6-cyclohexanehexol, inositols, cyclohexane-1,2,3,4,5,6-hexol
In biochemistry, medicine, and related sciences, inositol generally refers to '''myo-inositol (formerly meso-inositol'), the most important stereoisomer of the chemical compound cyclohexane-1,2,3,4,5,6-hexol. Its formula is ; the molecule has a ring of six carbon atoms, each with a hydrogen atom and a hydroxy group (–OH). In myo''-inositol, two of the hydroxyls, neither adjacent nor opposite, lie above the respective hydrogens relative to the mean plane of the ring.
OverviewAI-generated
Inositol is a chemical compound with the formula C₆H₁₂O₆. Its IUPAC name is cyclohexane-1,2,3,4,5,6-hexol. The substance has a mass of 180.063 and a density of 1.752. It melts at 226.
The compound features a charge of 0. It possesses six hydrogen bond donors and six hydrogen bond acceptors. The topological polar surface area is 121, and the xlogp value is -3.7. Inositol is referenced by 588 other encyclopedia articles.
Synthesized by Vinony from 20 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C6H12O6
- Molecular weight
- 180.16 g/mol
- IUPAC name
- cyclohexane-1,2,3,4,5,6-hexol
- SMILES
- C1(C(C(C(C(C1O)O)O)O)O)O
- InChIKey
- CDAISMWEOUEBRE-UHFFFAOYSA-N
- XLogP
- -3.7
- Polar surface area
- 121 Ų
- H-bond donors
- 6
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
53,190 papers- Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.Reproductive biology and endocrinology : RB&E · 2023
- Inositol as putative integrative treatment for PCOS.Reproductive biomedicine online · 2016
- D-Chiro-inositol and PCOS: between myth and reality. The never-ending story.International journal of food sciences and nutrition · 2022
- Update on the combination of myo-inositol/d-chiro-inositol for the treatment of polycystic ovary syndrome.Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2024
- Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review.Nutrients · 2023
via PubMed
~14 min read
Encyclopedic overview
17 sectionsContents
- History
- Chemical properties
- Physiological roles
- Biosynthesis
- Phytic acid in plants
- Biological function
- Industrial uses
- Explosives industry
- Road salt
- Research and clinical applications
- Trichotillomania
- Other illnesses
- Use as a cutting agent
- Nutritional sources
- Production
- References
- External links
In biochemistry, medicine, and related sciences, inositol generally refers to '''myo-inositol (formerly meso-inositol'), the most important stereoisomer of the chemical compound cyclohexane-1,2,3,4,5,6-hexol. Its formula is ; the molecule has a ring of six carbon atoms, each with a hydrogen atom and a hydroxy group (–OH). In myo-inositol, two of the hydroxyls, neither adjacent nor opposite, lie above the respective hydrogens relative to the mean plane of the ring.
The compound is a carbohydrate, specifically a sugar alcohol (as distinct from simple sugars like glucose) with half the sweetness of sucrose (table sugar). It is one of the most ancient components of living beings with multiple functions in eukaryotes, including structural lipids and secondary messengers. A human kidney makes about two grams per day from glucose, but other tissues synthesize it too. The highest concentration is in the brain, where it plays an important role in making other neurotransmitters and some steroid hormones bind to their receptors. In other tissues, it mediates cell signal transduction in response to a variety of hormones, neurotransmitters, and growth factors and participates in osmoregulation. In most mammalian cells the concentrations of myo-inositol are 5 to 500 times greater inside cells than outside them.
Excerpted from Wikipedia’s “inositol” article, available under the CC BY-SA 4.0 licence.