RGS4

Name

regulator of G protein signaling 4

Type

protein-coding

Position

163,068,775–163,076,802 (+)

Aliases

RGP4, SCZD9

Ensembl

ENSG00000117152

RefSeq RNA

NM_001102445.3, NM_001113380.1, NM_001113381.1, NM_005613.6

RefSeq protein

NP_001095915.1, NP_001106851.1, NP_001106852.1, NP_005604.1

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

regulator of G protein signaling 4

Symbol

RGS4

Biotype

Protein coding

Organism

Homo sapiens

Location

1:163,068,775-163,076,802

Strand

Forward (+)

Assembly

GRCh38