RORA

Name

RAR related orphan receptor A

Type

protein-coding

Position

60,488,284–61,229,302 (−)

Aliases

IDDECA, NR1F1, ROR1, ROR2, ROR3, RORa1, RORalpha, RZR-ALPHA, RZRA

Ensembl

ENSG00000069667

RefSeq RNA

NM_002943.4, NM_134260.3, NM_134261.3, NM_134262.3, XM_011521874.2

RefSeq protein

NP_002934.1, NP_599022.1, NP_599023.1, NP_599024.1, XP_011520176.1

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014].

via MyGene.info

Gene · Ensembl

RAR related orphan receptor A

Symbol

RORA

Biotype

Protein coding

Organism

Homo sapiens

Location

15:60,488,284-61,229,302

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein RORA PDB 1n83.png

via Wikidata · CC0