Also known as DELXp11.3, NM23-H10, NME10, TBCCD2, XRP2, retinitis pigmentosa 2 (X-linked recessive), RP2, ARL3 GTPase activating protein, RP2 activator of ARL3 GTPase
protein-coding gene in the species Homo sapiens
Gene data
RP2- Name
- RP2 activator of ARL3 GTPase
- Type
- protein-coding
- Chromosome
- X
- Position
- 46,836,922–46,889,240 (+)
- Aliases
- DELXp11.3, NM23-H10, NME10, TBCCD2, XRP2
- Ensembl
- ENSG00000102218
- RefSeq RNA
- NM_006915.3
- RefSeq protein
- NP_008846.2
The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RP2 activator of ARL3 GTPase
- Symbol
- RP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:46,836,922-46,889,240
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein RP2 PDB 2bx6.png
Show 5 more facts
- HomoloGene ID
- 5042
- genomic start
- 46696375
- exact match
- identifiers.org/ncbigene/6102
- genomic end
- 46741793
- cytogenetic location
- Xp11.3
Sources (4)
via Wikidata · CC0