RXRG
Sign in to saveAlso known as NR2B3, RXRC, Retinoid X receptor gamma, RXR-gamma, RXRgamma
protein-coding gene in the species Homo sapiens
Gene data
RXRG- Name
- retinoid X receptor gamma
- Type
- protein-coding
- Position
- 165,400,922–165,445,355 (−)
- Aliases
- NR2B3, RXR-gamma, RXRC, RXRgamma
- Ensembl
- ENSG00000143171
- RefSeq RNA
- NM_001256570.2, NM_001256571.2, NM_006917.5, NR_033824.2
- RefSeq protein
- NP_001243499.1, NP_001243500.1, NP_008848.1
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010].
Gene Ontology
Biological process
Molecular function
Pathways
PPAR signaling pathway - Homo sapiens (human)Th17 cell differentiation - Homo sapiens (human)Thyroid hormone signaling pathway - Homo sapiens (human)Adipocytokine signaling pathway - Homo sapiens (human)Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)Transcriptional misregulation in cancer - Homo sapiens (human)Thyroid cancer - Homo sapiens (human)Small cell lung cancer - Homo sapiens (human)Non-small cell lung cancer - Homo sapiens (human)
via MyGene.info
Wikidata facts
- Image
- Protein RXRG PDB 1by4.png
Show 5 more facts
- HomoloGene ID
- 21373
- exact match
- identifiers.org/ncbigene/6258
- genomic end
- 165414433
- genomic start
- 165400922
- cytogenetic location
- 1q23.3
Sources (8)
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 1
Entity
Ensembl genome database project
Entity
homeobox
Entity
PDX1
Gene
Wikidata
Entity
gene
Entity
chromosome
Entity
public domain
Entity
digital object identifier
Entity
vitamin A
Entity
human genome
Entity
Q229883
Entity
base pair
Entity
locus
Entity
gene expression
Entity
Online Mendelian Inheritance in Man
Entity
retinol
Entity
United States National Library of Medicine
Entity
transcription factor
Entity