Structure via PubChem · Public domain (PubChem)
(RS)-sertaconazole
Sign in to saveSertaconazole, sold under the brand name Ertaczo among others, is an antifungal medication of the Benzothiophene class. It is available as a cream to treat skin infections such as athlete's foot.
Chemical data
- Formula
- C20H15Cl3N2OS
- Molecular weight
- 437.8 g/mol
- IUPAC name
- 1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole
- SMILES
- C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl
- InChIKey
- JLGKQTAYUIMGRK-UHFFFAOYSA-N
- XLogP
- 6.3
- Polar surface area
- 55.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2003
- Admin. routes
- topical
- Indications
- atopic eczema
via ChEMBL · EBI
Research
3 papers- Fabrication and Characterization of Sertaconazole Nitrate Microsponge as a Topical Drug Delivery System.Indian journal of pharmaceutical sciences · 2015
- Comparative efficacy evaluation of different penetration enhancement strategies for dermal delivery of poorly soluble drugs - A case with sertaconazole nitrate.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2021
- A comparison of chiral resolution of antifungal agents on different polysaccharide chiral columns under various mobile phase modes: Application in the biological samples.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2021
via PubMed
Wikidata facts
- Subclass of
- medication
- Has part
- carbon
- Mass
- 435.997
Show 5 more facts
- chemical formula
- C₂₀H₁₅Cl₃N₂OS
- World Health Organisation international non-proprietary name
- sertaconazole
- canonical SMILES
- C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl
- subject has role
- antifungal
- Commons category
- Sertaconazole
Sources (2)
via Wikidata · CC0
~5 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Chemistry
- References
- External links
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464389376 | image = Sertaconazole.svg | image_class = skin-invert-image | width = | alt = | image2 = Sertaconazole ball-and-stick.png | image_class2 = bg-transparent | width2 = | alt2 =
| tradename = Ertaczo, Dermofix, Zalain | Drugs.com = | MedlinePlus = a608047 | DailyMedID = Sertaconazole | licence_US = Sertaconazole | pregnancy_US = C | legal_US = Rx-only | legal_status = Rx-only | routes_of_administration = Topical | ATC_prefix = D01 | ATC_suffix = AC14 | ATC_supplemental =
Excerpted from Wikipedia’s “(RS)-sertaconazole” article, available under the CC BY-SA 4.0 licence.